Is-dhexgalka Gaarka ah ee Goobta Si Sax ah Geli Hidde-yaasha Bartilmaameedka Meel Kulul oo Gaar ah
Is dhexgalka goobta-gaarka ah waa habka lagu habeynayo degel ama codsi si loo waafajiyo baahiyaha gaarka ah ee degel ama codsi gaar ah.Waa habraac ku lug leh in isbedel lagu sameeyo koodka jira iyo qaab dhismeedka website-ka ama codsiga si looga dhigo mid hufan oo waxtar u leh baahiyaha gaarka ah ee goobta.Is dhexgalka goobta-gaarka ah ayaa loo isticmaali karaa in lagu beddelo sifooyinka jira, lagu daro sifooyin cusub, oo loo wanaajiyo isticmaalka guud ee shabakada ama codsiga.Tani waxay si gaar ah faa'iido u leedahay ganacsiyada leh shabakado badan ama codsiyo u baahan in la isku daro si ay macaamiishooda u helaan khibrad aan kala go 'lahayn.
Isdhexgalka goobta gaarka ah ee unugyada CHO waa nidaam loo isticmaalo in lagu soo bandhigo hiddo-wadaha xiisaha meel si fiican loo qeexay oo ku jira genome-ka unugyada hamster-ka Shiinaha (CHO).Nidaamkani wuxuu ku lug leeyahay isticmaalka goobta-gaar ah recombinase enzyme si loo beegsado taxane gaar ah oo ku jira genome unugga CHO ka dibna la isku daro hidda-wadaha xiisaha ee taxanaha la beegsaday.Habkani wuxuu u oggolaanayaa in si sax ah loo xakameeyo gelinta hiddo-wadaha genome-ka unugga CHO wuxuuna kaa caawin karaa in laga fogaado is-dhexgalka aan tooska ahayn, kaas oo saameyn xun ku yeelan kara unugyada.Faa'iidooyinka ugu muhiimsan ee habkan ayaa ah in ay bixiso xakameyn weyn iyo saxnaanta habka isdhexgalka, iyo sidoo kale heerka xasilloonida ee hiddaha waqti ka dib.Intaa waxa dheer, habkan waxa loo isticmaali karaa in lagu soo bandhigo hiddo-wadeyaal badan meelo kala duwan oo unugga dhexdiisa ah, taas oo ka dhigaysa qalab awood badan oo wax lagaga qabanayo hidde-sidaha.
Beegsatada bartilmaameedsanaysa
Beegsiga bartilmaameedyada waxaa loo isticmaalaa in lagu abuuro noole hidde ahaan wax laga beddelay iyada oo la soo bandhigayo taxane DNA oo gaar ah genomygooda.Waxay caadi ahaan ka kooban yihiin calaamade hidde-sidaha oo u oggolaanaya aqoonsiga unugyada la beddelay, calaamad la dooran karo oo u oggolaanaysa xulashada unugyada la beddelay, iyo gobolka dib-u-habaynta isku-dhafka ah ee u oggolaanaya isku-dhafka DNA-da ee la rabo ee genome-ka noolaha ee bartilmaameedka ah.Bartilmaameedka xididada waxaa badanaa loo isticmaalaa garaacista hidda-socodka, garaacista hidda-wadaha, tafatirka hidda-wadaha, iyo noocyada kale ee injineernimada hidde-sidaha.
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